This paper presents an educational setting that attempts to enhance students’ understanding and facilitate students’ linking-inferencing skills. The proposed setting is structured in three stages. The first stage intends to explore students’ prior knowledge. The second stage aims to help students tackle their difficulties and misconceptions and deepen their understanding of the topics under study. This is attempted through individual student engagement in suitably-designed activities and relative feedback. As recorded in previous research, students’ difficulties feedback on the material development. The third stage of the educational setting exploits social interaction to help students reorganize their knowledge of the concepts under study. The web-based application of the proposed educational setting indicated improvement in first-year Computer Science (CS) students’ understanding of fundamental Computer Architecture concepts and progress in students’ linking-inference skills. These results encourage integration in the instructional process of interventions designed according to the proposed setting in order to support and enhance students’ understanding of troublesome concepts and their interrelations.